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In the Transmissions is shown that Adam abused of his daughter (physically or emotionally) before going to PATHOS-II. It's clearly shown that Adam feels remorse of what he has done, mainly because he constantly sees his daughter recorded messages and has vivid hallucinations of her.
Melissa's fate is left unclear in the rest of the Transmissions, but it's certain that she died in the Impact Event, as long as the rest of the Earth.